C H A P T E R 4 Table 2: Height, weight and corresponding BMI values of the 3rd, 50th and 97th percentile of a 4-‐year, 68 resp. 10-‐year old boy. Height (cm) Ideal Weight (kg) BMI (kg/m2 ) Boy, 4 years P3 99 14.2 14.5 P50 107 17.7 15.5 P97 115 21.3 16.1 Boy, 10 years P3 129 24.7 14.8 P50 141 30 15.1 P97 152 37.5 16.3 Increase in BMI is an extra risk factor for SGA children, because if this value in-‐ creases in children with a relative short length, the increase in weight is relatively higher than in children with a higher length who show a same increase in BMI. For health care practitioners it is important to be aware that BMI, as well as weight for height values, should not change in SGA children after rhGH treatment to pre-‐ vent the risk of developing the metabolic syndrome. According to the results of this study, it is reasonable to use cut-‐off values; a difference in BMI of +/-‐ 1.0 and an increase or decrease of 0.4 SDS in weight for height is acceptable. Conclusion During the first year of rhGH treatment, the BMI and weight for height of SGA chil-‐ dren barely change. The detected slight increase in TBW in SGA children is based on an increase in FFM and not in FM. This means that the body composition in SGA children improves after receiving rhGH treatment. This treatment contributes in the prevention of the metabolic syndrome in SGA children. For health care practi-‐ tioners it is important to monitor that BMI, as well as weight for height values should not change in SGA children, after rhGH treatment.
Proefschrift binnenwerk Manon Ernst_DEF.indd
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