Chapter 2 The search was limited to articles published from 1975‐2012 in the English, German and Dutch language. Initially, the titles and abstracts of the retrieved articles were screened. Secondly, the full text of potentially appropriate articles was printed and read. Reference lists were cross‐checked for additional eligible papers. Figure 2.1 shows a flowchart of the article selection. Studies were eligible if they reported on novel optical imaging methods in laparoscopic gastrointestinal surgery, but also gynecologic and urologic procedures were included. Studies were excluded if they did not report on anatomical identification or tissue characterization using new optical imaging techniques, described a study protocol, or could not be retrieved in full length. First, the literature search and study selection was conducted by two authors (R.M.S. and L.P.S.) independently. After discussion, consensus was reached on the final inclusion for this review. Figure 2.1 Flowchart for selection of articles 20 Potentially relevant studies identified by first search in PubMed database n=248 Studies excluded after title/abstract screening (reviews, congress abstracts, non‐surgical, other irrelevant topic) n=181 Studies included for reading whole article n=67 Studies excluded after reading whole article (radiology, flexible endoscopy, only on tumor targeted imaging) n=25 New references identified n=10 Studies used for review n=52
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