Blood pressure corrected evoked flow responses Table 2 Median (25-75%) NVC parameter values for RG and RGCA model for averaged mean and systolic CBFV responses. CA parameter values for RGCA model. N=71, * p<0.01 Before correc- After correction Before correc- After correc- tion (mean CBFV) tion tion (mean CBFV) (systolic CBFV) (systolic CBFV) ! rad/s 0.18 (0.13-0.26) 0.18 (0.14-0.24) 0.18 (0.14-0.27) 0.19 (0.14-0.31) 0.78 (0.57-1.2) 0.74 (0.56-1.0) * 0.76 (0.63-1.4) 0.81 (0.59-1.2) Tv s 8 (3-27) 7 (3-17) 7 (3-18) 6 (3-14) K 23 (17-31) 25 (18-31) 23 (18-29) 23 (18-30) K3 2.4 (1.7-3.6) 1.8 (1.0-2.7) K2 0.98 (0.63-1.0) 1.0 (0.81-1.0) T s 1.3 (0.97-1.8) 1.1 (0.68-2.0) D 0.58 (0.5-1.3) 0.5 (0.5-0.61) ARI 5.4 (4.6-6.3) 6.2 (4.5-8.2) Table 2 shows group median NVC parameters before and after blood pressure correction. It also shows median CA parameter values for the blood pressure corrected model. No significant differences in NVC parameters were found except for (mean). Blood pressure correction resulted in a small but significant decrease of median (25-75 percentiles) from 0.8 (0.6-1.2) without to 0.7 (0.6-1.0) (p<0.01) with correction. However if average parameter values do not change significantly, individual values may have changed. To show individual parameter changes Bland-Altman plots are shown in figure 5. In each subplot the difference between uncorrected and corrected values are plotted against the average of both for each of the four parameters! (A), (B), Tv (C) and K (D). The crosses repre- sent estimated parameters on mean and the circles on systolic evoked responses. These plots show the number of parameters that are increased after correction roughly equal the amount of parameters that are decreased after blood pressure correction. 89
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