Chapter 6 Table 2 Cerebral autoregulation parameters during CPB; mean (std) paCO2 30 mmHg 40 mmHg 50 mmHg n=36 n=37 n=37 Mean ABP mmHg 76 (11) 80 (11) 80 (10) Std ABP mmHg 7.4 (3) 7.0 (3) 7.4 (3) PSD ABP at 0.1 Hz 0.58 (0.4) 0.65 (0.4) 0.81 (0.5) b* c** mmHg2/Hz *1000 Mean CBFV left cm/s 25 (11) 33 (12) 48 (17) a** b** c** Std CBFV left cm/s 3.6 (1) 3.9 (1) 5.2 (3) b** c* PSD CBFV left at 0.1 Hz 0.33 (0.2) 0.30 (0.2) 0.33 (0.3) (cm/s)2/Hz *1000 Mean CBFV right cm/s 24 (8) 32 (11) 46 (16) a** b** c** Std CBFV right cm/s 3.4 (1) 3.8 (2) 4.8 (2) b** c* PSD CBFV right @ 0.1 Hz 0.28 (0.2) 0.30 (0.3) 0.36 (0.3) (cm/s)2/Hz *1000 Hct % 27 (4) CO2 Reactivity TCD 2.5 (1) 5.0 (2) b** %/mmHg SctO2 NIRS % 65 (4) 66 (4) 69 (3) a** b** c** CO2 Reactivity NIRS 0.25 (0.3) 0.45 (0.3) b* %/mmHg Coherence at 0.1 Hz 0.90 (0.1) 0.91 (0.09) 0.95 (0.06) b* c* Gain at 0.1 Hz %/mmHg 3.4 (2) 2.2 (0.9) 1.4 (0.4) a** b** c** Phase at 0.1 Hz rad 0.58 (0.3) 0.31 (0.2) 0.10 (0.1) a** b** c** ARI 5.8 (1) 4.8 (1) 3.0 (2) a** b** c** a (30 vs. 40 mmHg), b (30 vs. 50 mmHg), c (40 vs. 50 mmHg), * p < 0.05 ** p<0.01 after Bonferroni correction 108
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