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Single centre experience of surgical and endovascular treatment 95 Table 6 shows the findings at follow-up imaging in aneurysms which had undergone endovascular treatment. Follow-up angiography was available for 181 surviving patients (95.3%, harboring 189 aneurysms). The average interval between treatment and the last angiographic follow-up was 29.1 months (range 4.8-102.8 months). Increasing compaction of the coil mass was observed in 72 aneurysms (38.1%); this occurred more often in the group that showed a residual aneurysm at the end of the procedure (52.0%) than in those with complete occlusion (36.8%) or a residual neck (34.0%) determined at post-procedural angiography. However, this difference was not statistically significant (p=0.124). Table 6. Angiographic FU after endovascular treatment by post-procedural angiographic results Increased Post procedural angiographic No changes Improvement recanalization results Number (%) Number (%) Number (%) Complete occlusion (n=114) 72 (63.2) - 42 (36.8) Residual neck (n=50) 24 (48.0) 9 (18.0) 17 (34.0) Residual aneurysm (n=25) 12 (48.0) - 13 (52.0) Total 189 108 (57.1) 9(4.8) 72 (38.1) Re-treatment was performed in 16 aneurysms in the endovascular group, 2 after rebleeding and 14 without rebleeding. At the end of the first procedure 10 of these showed a residual aneurysm, 4 aneurysms a residual neck, and 2 were completely occluded after coiling. Rebleeds After the procedure, rebleeding from the target aneurysm occurred in 12 aneurysms. Six (2.5%) occurred after endovascular treatment, and 6 (3.0%) after surgical treatment. This difference is not statistically significant (p=0.769). Four patients from the endovascular treatment group had a residual aneurysm shown by post- procedural imaging, and 2 had a residual neck. In the endovascular group the presence of a residual neck after coiling was not related to rebleeding (p=0.085). The presence of a residual aneurysm after coiling was statistically significantly related to rebleeding (p=0.001). One of the surgically treated patients mentioned above had a residual aneurysm; the other 5 did not undergo post-procedural angiography. Because of the missing data no analysis could be performed on the surgically treated aneurysms. Outcome of rebleeds was poor (Table 7).


proefschrit Van Zwam inhoud met kaft en stellingen.indd
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