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98 Chapter 5 of patients at the time of presentation is taken into account. Furthermore, the rates of dependency are low in both treatment groups. Coiling results in lower rates of complete aneurysm occlusion compared with surgical treatment. Post-coiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding. References 1 Rinkel, G. J., Djibuti, M., Algra, A. & van Gijn, J. Prevalence and risk of rupture of intracranial aneurysms: a systematic review. Stroke 29, 251-256, (1998). 2 Guglielmi, G., Vinuela, F., Dion, J. & Duckwiler, G. Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience. J Neurosurg 75, 8-14, (1991). 3 Guglielmi, G., Vinuela, F., Sepetka, I. & Macellari, V. Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results. J Neurosurg 75, 1-7, (1991). 4 Molyneux, A. et al. International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet 360, 1267-1274, (2002). 5 Molyneux, A. J. et al. Risk of recurrent subarachnoid haemorrhage, death, or dependence and standardised mortality ratios after clipping or coiling of an intracranial aneurysm in the International Subarachnoid Aneurysm Trial (ISAT): long-term follow-up. Lancet Neurol 8, 427-433, (2009). 6 Molyneux, A. J. et al. International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 366, 809- 817, (2005). 7 Raja, P. V. et al. Microsurgical clipping and endovascular coiling of intracranial aneurysms: a critical review of the literature. Neurosurgery 62, 1187-1202; discussion 1202-1183, (2008). 8 Grunwald, I. Q. et al. Recanalization after endovascular treatment of intracerebral aneurysms. Neuroradiology 49, 41-47, (2007). 9 Holmin, S. et al. Intradural saccular aneurysms treated by Guglielmi detachable bare coils at a single institution between 1993 and 2005: clinical long-term follow-up for a total of 1810 patient-years in relation to morphological treatment results. Stroke 39, 2288-2297, (2008). 10 Lot, G., Houdart, E., Cophignon, J., Casasco, A. & George, B. Combined management of intracranial aneurysms by surgical and endovascular treatment. Modalities and results from a series of 395 cases. Acta Neurochir (Wien) 141, 557-562, (1999). 11 Raymond, J. et al. Long-term angiographic recurrences after selective endovascular treatment of aneurysms with detachable coils. Stroke 34, 1398-1403, (2003). 12 Hunt, W. E. & Hess, R. M. Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J Neurosurg 28, 14-20, (1968). 13 Kasner, S. E. Clinical interpretation and use of stroke scales. Lancet Neurol 5, 603-612, (2006). 14 Roy, D., Milot, G. & Raymond, J. Endovascular treatment of unruptured aneurysms. Stroke 32, 1998-2004, (2001). 15 Johnston, S. C. et al. Predictors of rehemorrhage after treatment of ruptured intracranial aneurysms: the Cerebral Aneurysm Rerupture After Treatment (CARAT) study. Stroke 39, 120-125, (2008). 16 Willinsky, R. A. et al. Clinical and angiographic follow-up of ruptured intracranial aneurysms treated with endovascular embolization. AJNR Am J Neuroradiol 30, 1035-1040, (2009). 17 Aikawa, H. et al. Rebleeding after endovascular embolization of ruptured cerebral aneurysms. Neurol Med Chir (Tokyo) 47, 439-445; discussion 446-437, (2007). 18 Sluzewski, M. & van Rooij, W. J. Early rebleeding after coiling of ruptured cerebral aneurysms: incidence, morbidity, and risk factors. AJNR Am J Neuroradiol 26, 1739-1743, (2005). 19 Sluzewski, M., van Rooij, W. J., Beute, G. N. & Nijssen, P. C. Late rebleeding of ruptured intracranial aneurysms treated with detachable coils. AJNR Am J Neuroradiol 26, 2542-2549, (2005). 20 Tsutsumi, K., Ueki, K., Usui, M., Kwak, S. & Kirino, T. Risk of recurrent subarachnoid hemorrhage after complete obliteration of cerebral aneurysms. Stroke 29, 2511-2513, (1998).


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